Ruud Leemans: search on Z-Library

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1

Protein biomarker discovery for head and neck cancer

Tieneke B.M. Schaaij-Visser, Ruud H. Brakenhoff, C. René Leemans, Albert J.R. Heck, Monique Slijper

Journal:

Journal of Proteomics

Year:

2010

Language:

english

File:

PDF, 580 KB

english, 2010

2

The molecular landscape of head and neck cancer

Leemans, C. René, Snijders, Peter J. F., Brakenhoff, Ruud H.

Journal:

Nature Reviews Cancer

Year:

2018

Language:

english

File:

PDF, 691 KB

english, 2018

3

The molecular biology of head and neck cancer

Leemans, C. René, Braakhuis, Boudewijn J. M., Brakenhoff, Ruud H.

Journal:

Nature Reviews Cancer

Year:

2010

Language:

english

File:

PDF, 769 KB

english, 2010

4

Multiple Head and Neck Tumors Frequently Originate from a Single Preneoplastic Lesion

Maarten P. Tabor, Ruud H. Brakenhoff, Henrique J. Ruijter-Schippers, Jacqueline E. van der Wal, Gordon B. Snow, C. René Leemans, Boudewijn J.M. Braakhuis

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 262 KB

english, 2002

5

A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen

Serge J. Smeets, Albertus T. Hesselink, Ernst-Jan M. Speel, Annick Haesevoets, Peter J.F. Snijders, Michael Pawlita, Chris J.L.M. Meijer, Boudewijn J.M. Braakhuis, C. René Leemans, Ruud H. Brakenhoff

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 286 KB

english, 2007

6

Molecular analysis of surgical margins in head and neck cancer: More than a marginal issue

Boudewijn J.M. Braakhuis, Elisabeth Bloemena, C. René Leemans, Ruud H. Brakenhoff

Journal:

Year:

2010

Language:

english

File:

PDF, 168 KB

english, 2010

7

Discordance of genetic alterations between primary head and neck tumors and corresponding metastases associated with mutational status of the TP53 gene

Maarten P. Tabor, Viola M. M. van Houten, J. Alain Kummer, Maria J. W. D. Vosjan, Ronald Vlasblom, Gordon B. Snow, C. René Leemans, Boudewijn J. M. Braakhuis, Ruud H. Brakenhoff

Journal:

Genes, Chromosomes and Cancer

Year:

2002

Language:

english

File:

PDF, 271 KB

english, 2002

8

Second primary tumors and field cancerization in oral and oropharyngeal cancer: Molecular techniques provide new insights and definitions

Boudewijn J.M. Braakhuis, Maarten P. Tabor, C. René Leemans, Isaac van der Waal, Gordon B. Snow, Ruud H. Brakenhoff

Journal:

Year:

2002

Language:

english

File:

PDF, 168 KB

english, 2002

9

Mutated p53 as a molecular marker for the diagnosis of head and neck cancer

Viola MM van Houten, Maarten P Tabor, Michiel WM van den Brekel, J Alain Kummer, Fedor Denkers, Janny Dijkstra, René Leemans, Isaäc van der Waal, Gordon B Snow, Ruud H Brakenhoff

Journal:

The Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 315 KB

english, 2002

10

Status of primary tumour surgical margins in squamous head and neck cancer: prognostic implications

Bradley, Patrick J, MacLennan, Kenneth, Brakenhoff, Ruud H, Leemans, C René

Journal:

Current Opinion in Otolaryngology & Head & Neck Surgery

Year:

2007

Language:

english

File:

PDF, 126 KB

english, 2007

11

Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass

van Harten, Anne M., Poell, Jos B., Buijze, Marijke, Brink, Arjen, Wells, Susanne I., René Leemans, C., Wolthuis, Rob M.F., Brakenhoff, Ruud H.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.59 MB

english, 2019

12

Wait-and-see policy for the N0 neck in early-stage oral and oropharyngeal squamous cell carcinoma using ultrasonography-guided cytology: Is there a role for identification of the sentinel node?

Eline J. C. Nieuwenhuis, Jonas A. Castelijns, Rik Pijpers, Michiel W. M. van den Brekel, Ruud H. Brakenhoff, Isaac van der Waal, Gordon B. Snow, Charles R. Leemans

Journal:

Year:

2002

Language:

english

File:

PDF, 113 KB

english, 2002

13

Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass

van Harten, Anne M., Poell, Jos B., Buijze, Marijke, Brink, Arjen, Wells, Susanne I., René Leemans, C., Wolthuis, Rob M.F., Brakenhoff, Ruud H.

Journal:

Year:

2019

File:

PDF, 2.59 MB

2019

14

Molecular Characterization of Locally Relapsed Head and Neck Cancer after Concomitant Chemoradiotherapy

de Roest, Reinout H., Mes, Steven W., Poell, Jos B., Brink, Arjen, van de Wiel, Mark A., Bloemena, Elisabeth, Thai, Elena, Poli, Tito, Leemans, C. René, Brakenhoff, Ruud H.

Journal:

Clinical Cancer Research

Year:

2019

File:

PDF, 680 KB

2019

15

Response to correspondence on the molecular biology of head and neck cancer

Leemans, C. René, Braakhuis, Boudewijn J. M., Brakenhoff, Ruud H.

Journal:

Nature Reviews Cancer

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

16

Human papilloma virus in head and neck cancer: The need for a standardised assay to assess the full clinical importance

Boudewijn J.M. Braakhuis, Ruud H. Brakenhoff, Chris J.L.M. Meijer, Peter J.F. Snijders, C. René Leemans

Journal:

European Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 118 KB

english, 2009

17

Protein signatures associated with tumor cell dissemination in head and neck cancer

Onno B. Bleijerveld, Ruud H. Brakenhoff, Tieneke B.M. Schaaij-Visser, J. Mirjam A. Damen, A.F. Maarten Altelaar, Albert J.R. Heck, C. René Leemans, Monique Slijper

Journal:

Journal of Proteomics

Year:

2011

Language:

english

File:

PDF, 871 KB

english, 2011

18

Expanding fields of genetically altered cells in head and neck squamous carcinogenesis

Boudewijn J.M. Braakhuis, C. René Leemans, Ruud H. Brakenhoff

Journal:

Seminars in Cancer Biology

Year:

2005

Language:

english

File:

PDF, 228 KB

english, 2005

19

Using tissue adjacent to carcinoma as a normal control: an obvious but questionable practice

Boudewijn JM Braakhuis, C René Leemans, Ruud H Brakenhoff

Journal:

The Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 58 KB

english, 2004

20

Prognostic value of DNA ploidy status in patients with oral leukoplakia

Jantine F. Bremmer, Ruud H. Brakenhoff, Mark A.M. Broeckaert, Jeroen A.M. Beliën, C. René Leemans, Elisabeth Bloemena, Isaäc van der Waal, Boudewijn J.M. Braakhuis

Journal:

Year:

2011

Language:

english

File:

PDF, 250 KB

english, 2011

21

The Additional Value of Ultrafast DCE-MRI to DWI-MRI and 18F-FDG-PET to Detect Occult Primary Head and Neck Squamous Cell Carcinoma

Martens, Roland M., Stappen, Ruud van der, Koopman, Thomas, Noij, Daniel P., Comans, Emile F., Zwezerijnen, Gerben J., Vergeer, Marije R., Leemans, C. RenÃ©, de Bree, Remco, Boellaard, Ronald, Casteli

Journal:

Year:

2020

File:

PDF, 727 KB

2020

22

An investigation into the crystallisation behaviour of an amorphous cryomilled pharmaceutical material above and below the glass transition temperature

Sheng Qi, Ilse Weuts, Steve De Cort, Sigrid Stokbroekx, Ruud Leemans, Mike Reading, Peter Belton, Duncan Q.M. Craig

Journal:

Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 412 KB

english, 2010

23

Outcome of patients with early stage oral cancer managed by an observation strategy towards the N0 neck using ultrasound guided fine needle aspiration cytology: No survival difference as compared to elective neck dissection

Flach, Géke B., Tenhagen, Mark, de Bree, Remco, Brakenhoff, Ruud H., van der Waal, Isaac, Bloemena, Elisabeth, Kuik, Dirk J., Castelijns, Jonas A., René Leemans, C.

Journal:

Year:

2013

Language:

english

File:

PDF, 302 KB

english, 2013

24

A genetic progression model of oral cancer: current evidence and clinical implications

Boudewijn J. M. Braakhuis, C. René Leemans, Ruud H. Brakenhoff

Journal:

Journal of Oral Pathology & Medicine

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

25

Effects of Different Meal Compositions and Fasted State on the Oral Bioavailability of Etravirine

Dr. Monika Schöller-Gyüre, Dr. Marta Boffito, Dr. Anton L. Pozniak, Mr. Ruud Leemans, Dr. Thomas N. Kakuda, Dr. Brian Woodfall, Ms. Veerle Vyncke, Ms. Monika Peeters, Ms. Kati Vandermeulen, Dr. Richar

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

2008

Language:

english

File:

PDF, 151 KB

english, 2008

26

Sensitivity to chromosomal breakage as risk factor in young adults with oral squamous cell carcinoma

Braakhuis, Boudewijn J. M., Nieuwint, Aggie W. M., Oostra, Anneke B., Joenje, Hans, Flach, Géke B., Graveland, A. Peggy, Brakenhoff, Ruud H., Leemans, C. René

Journal:

Journal of Oral Pathology & Medicine

Year:

2016

Language:

english

File:

PDF, 74 KB

english, 2016

27

A review of the most promising biomarkers for early diagnosis and prognosis prediction of tongue squamous cell carcinoma

Hussein, Aisha A., Forouzanfar, Tymour, Bloemena, Elisabeth, de Visscher, JGAM, Brakenhoff, Ruud H., Leemans, C. René, Helder, Marco N.

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 572 KB

english, 2018

28

Adenovirus retargeting to surface expressed antigens on oral mucosa

Hester J. T. van Zeeburg, Victor W. van Beusechem, Aafke Huizenga, Hidde J. Haisma, Nick Korokhov, Susan Gibbs, C. René Leemans, Ruud H. Brakenhoff

Journal:

The Journal of Gene Medicine

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

29

Genomic profiling identifies common HPV-associated chromosomal alterations in squamous cell carcinomas of cervix and head and neck

Saskia M Wilting, Serge J Smeets, Peter JF Snijders, Wessel N van Wieringen, Mark A van de Wiel, Gerrit A Meijer, Bauke Ylstra, C René Leemans, Chris JLM Meijer, Ruud H Brakenhoff, Boudewijn JM Braakh

Journal:

BMC Medical Genomics

Year:

2009

Language:

english

File:

PDF, 2.13 MB

english, 2009

30

The internal anatomy of the face

Flach, Géke B., Tenhagen, Mark, de Bree, Remco, Brakenhoff, Ruud H., van der Waal, Isaac, Bloemena, Elisabeth, Kuik, Dirk J., Castelijns, Jonas A., René Leemans, C.

Journal:

International Journal of Orthodontia

Year:

1917

Language:

english

File:

PDF, 178 KB

english, 1917

31

Applications of molecular diagnostics for personalized treatment of head and neck cancer: state of the art

Mes, Steven W., Leemans, C. René, Brakenhoff, Ruud H.

Journal:

Expert Review of Molecular Diagnostics

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

32

Cancer stem cell enrichment marker CD98: A prognostic factor for survival in patients with human papillomavirus-positive oropharyngeal cancer

Rietbergen, Michelle M., Martens-de Kemp, Sanne R., Bloemena, Elisabeth, Witte, Birgit I., Brink, Arjen, Baatenburg de Jong, Robert J., Leemans, C. René, Braakhuis, Boudewijn J.M., Brakenhoff, Ruud H.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 1.48 MB

english, 2014

33

Pharmacokinetics and short-term safety and tolerability of etravirine in treatment-experienced HIV-1-infected children and adolescents

Königs, Christoph, Feiterna-Sperling, Cornelia, Esposito, Susanna, Viscoli, Claudio, Rosso, Raffaella, Kakuda, Thomas N., Leemans, Ruud, Peeters, Monika, Mack, Rebecca, Peeters, Ingeborg, Sinha, Rekha

Journal:

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

34

The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics

Martens-de Kemp, Sanne R., Brink, Arjen, van der Meulen, Ida H., de Menezes, Renée X., te Beest, Dennis E., Leemans, C. René, van Beusechem, Victor W., Braakhuis, Boudewijn J.M., Brakenhoff, Ruud H.

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 976 KB

english, 2017

35

Establishment and Genetic Landscape of Precancer Cell Model Systems from the Head and Neck Mucosal Lining

de Boer, D. Vicky, Brink, Arjen, Buijze, Marijke, Stigter-van Walsum, Marijke, Hunter, Keith D, Ylstra, Bauke, Bloemena, Elisabeth, Leemans, C. René, Brakenhoff, Ruud H.

Journal:

Molecular Cancer Research

Year:

2018

Language:

english

File:

PDF, 3.47 MB

english, 2018

36

Physicochemical properties of the amorphous drug, cast films, and spray dried powders to predict formulation probability of success for solid dispersions: Etravirine

Ilse Weuts, Frederic Van Dycke, Jody Voorspoels, Steve De Cort, Sigrid Stokbroekx, Ruud Leemans, Marcus E. Brewster, Dawei Xu, Brigitte Segmuller, Ya Tsz A. Turner, Clive J. Roberts, Martyn C. Davies,

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

37

Comparative evaluation of genetic assays to identify oral pre-cancerous fields

Jantine F. Bremmer, Boudewijn J. M. Braakhuis, Arjen Brink, Mark A. M. Broeckaert, Jeroen A. M. Beliën, Gerrit A. Meijer, Dirk J. Kuik, C. René Leemans, Elisabeth Bloemena, Isaäc Van Der Waal, Ruud H.

Journal:

Journal of Oral Pathology & Medicine

Year:

2008

Language:

english

File:

PDF, 329 KB

english, 2008

38

Digital pathology-aided assessment of tumor-infiltrating T lymphocytes in advanced stage, HPV-negative head and neck tumors

de Ruiter, Emma J., de Roest, Reinout H., Brakenhoff, Ruud H., Leemans, C. RenÃ©, de Bree, Remco, Terhaard, Chris H. J., Willems, Stefan M.

Journal:

Cancer Immunology, Immunotherapy

Year:

2020

Language:

english

File:

PDF, 1.56 MB

english, 2020

39

Corrigendum to “Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging” [Radiother Oncol 113 (2014) 324–30]

Velazquez, Emmanuel Rios, Hoebers, Frank, Aerts, Hugo J.W.L., Rietbergen, Michelle M., Brakenhoff, Ruud H., Leemans, René C., Speel, Ernst-Jan, Straetmans, Jos, Kremer, Bernd, Lambin, Philippe

Journal:

Radiotherapy and Oncology

Year:

2017

Language:

english

File:

PDF, 313 KB

english, 2017

40

Epithelial-to-mesenchymal transition is a prognostic marker for patient outcome in advanced stage HNSCC patients treated with chemoradiotherapy

van der Heijden, Martijn, Essers, Paul B.M., Verhagen, Caroline V.M., Willems, Stefan M., Sanders, Joyce, de Roest, Reinout H., Vossen, David M., Leemans, C. RenÃ©, Verheij, Marcel, Brakenhoff, Ruud H

Journal:

Radiotherapy and Oncology

Year:

2020

File:

PDF, 1.47 MB

2020

41

Comprehensive multiparameter genetic analysis improves circulating tumor DNA detection in head and neck cancer patients

Mes, Steven W., Brink, Arjen, Sistermans, Erik A., Straver, Roy, Oudejans, Cees B.M., Poell, Jos B., Leemans, C. RenÃ©, Brakenhoff, Ruud H.

Journal:

Year:

2020

File:

PDF, 1.24 MB

2020

42

Ovarian cancer derived copy number alterations signatures are prognostic in chemoradiotherapy treated head and neck squamous cell carcinoma

Essers, Paul B.M., Heijden, Martijn, Vossen, David, Roest, Reinout H., Leemans, C. RenÃ©, Brakenhoff, Ruud H., Brekel, Michiel W.M., Bartelink, Harry, Verheij, Marcel, Vens, Conchita

Journal:

International Journal of Cancer

Year:

2020

File:

PDF, 1.22 MB

2020

43

Loss of heterozygosity at 9p and p53 immunopositivity in surgical margins predict local relapse in head and neck squamous cell carcinoma

A. Peggy Graveland, Pawel J. Golusinski, Marijke Buijze, Rinze Douma, Nanet Sons, Dirk J. Kuik, Elisabeth Bloemena, C. René Leemans, Ruud H. Brakenhoff, Boudewijn J.M. Braakhuis

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 317 KB

english, 2011

44

Gene expression profiling in head and neck squamous cell carcinoma

Braakhuis, Boudewijn JM, Brakenhoff, Ruud H, Leemans, C René

Journal:

Current Opinion in Otolaryngology & Head & Neck Surgery

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

45

Development and validation of a novel and rapid molecular detection method for high-risk HPV in formalin-fixed paraffin-embedded tumor tissue

Mes, Steven W., Heideman, Daniëlle A.M., Bloemena, Elisabeth, Brink, Arjen, Bogaarts, Martijn, Leemans, C. René, Brakenhoff, Ruud H.

Journal:

The Journal of Molecular Diagnostics

Year:

2019

File:

PDF, 1.51 MB

2019

46

Histopathologic validation of the sentinel node concept in oral and oropharyngeal squamous cell carcinoma

Eline J. C. Nieuwenhuis, Isaac van der Waal, C. René Leemans, Alain Kummer, Rik Pijpers, Jonas A. Castelijns, Ruud H. Brakenhoff, Gordon B. J. Snow

Journal:

Year:

2005

Language:

english

File:

PDF, 256 KB

english, 2005

47

Comparative molecular and histological grading of epithelial dysplasia of the oral cavity and the oropharynx

Maarten P Tabor, Boudewijn JM Braakhuis, Jacqueline E van der Wal, Paul J van Diest, C René Leemans, Ruud H Brakenhoff, J Alain Kummer

Journal:

The Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

48

Generation of precursor cell lines from preneoplastic fields surrounding head and neck cancers

Hester J.T. van Zeeburg, A. Peggy Graveland, Arjen Brink, Melanie Nguyen, C. René Leemans, Elisabeth Bloemena, Boudewijn J.M. Braakhuis, Ruud H. Brakenhoff

Journal:

Year:

2012

Language:

english

File:

PDF, 507 KB

english, 2012

49

A comprehensive assessment protocol including patient reported outcomes, physical tests, and biological sampling in newly diagnosed patients with head and neck cancer: is it feasible?

van Nieuwenhuizen, Annette J., Buffart, Laurien M., Smit, Jan H., Brakenhoff, Ruud H., Braakhuis, Boudewijn J. M., de Bree, Remco, Leemans, C. René, Verdonck-de Leeuw, Irma M.

Journal:

Supportive Care in Cancer

Year:

2014

Language:

english

File:

PDF, 254 KB

english, 2014

50

Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging

Rios Velazquez, Emmanuel, Hoebers, Frank, Aerts, Hugo J.W.L., Rietbergen, Michelle M., Brakenhoff, Ruud H., Leemans, René C., Speel, Ernst-Jan, Straetmans, Jos, Kremer, Bernd, Lambin, Philippe

Journal:

Radiotherapy and Oncology

Year:

2014

Language:

english

File:

PDF, 782 KB

english, 2014

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